The mRNA degrees of HSP60 and Clpp were also drastically low in HD patient-derived fibroblasts (Figs. (mtHtt) inhibits the mtUPR by impairing ABCB10 mRNA balance. These results demonstrate a suppression from the UPRmt by mtHtt, recommending that CPI-203 disturbance of mitochondrial protein quality control might donate to the pathogenesis of […]
Daily Archives: April 24, 2022
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