McMurtry MS, Archer SL, Altieri DC, Bonnet S, Haromy A, Harry G, et al. mice,[47] and hypoxia increases expression in mouse PA endothelial cells. In an interesting intersection with metabolic therapies for PAH, mice overexpressing the serotonin transporter benefit by treatment with the pyruvate dehydrogenase kinase (PDK) inhibitor, dicholoroacetate.[48] gene-modified […]